Weekend trip by car from Brussels?

La Baie de Somme: walking and the coast, https://www.somme-tourisme.com/la-baie-de-somme
Reims: Champagne houses, https://www.reims-tourism.com/
Troyes: medieval art and history, https://www.champagne-ardenne-tourism.co.uk/
Les Vosges: skiing, walking, nature, http://www.tourisme.vosges.fr/
Alsace: wine, gastronomy, walking, historic towsn, https://www.tourisme-alsace.com/en

Have you explored all of Belgium? Brugge is lovely as is the Ardennes. Also since you don’t say what you’re interested in you could end up in hell, do you love culture, beaches, walking, cities you don’t say how can anyone really offer ideas?